Research Grants for the Primary or Secondary Prevention of Opioid Overdose (R01)

Description

The awards pursuant to this Notice of Funding Opportunity are contingent upon the availability of funds.The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research that will help expand and advance our understanding about what works to prevent overdose from prescription and illicit opioids by developing and piloting, or rigorously evaluating novel primary or secondary prevention interventions.The intent of this Notice of Funding Opportunity (NOFO) is to: (1) build the scientific base for the primary or secondary prevention of opioid overdose, and (2) encourage collaboration of scientists from a spectrum of disciplines including public health, epidemiology, law enforcement, social work, economics, and criminal justice to perform research that can identify ways to prevent opioid overdose more effectively. Interventions can be strategies, programs, or policies. Ultimately, this research is intended to improve state and local health departments’ ability to implement and improve interventions focused on preventing opioid-related deaths.Researchers are expected to develop and pilot, or rigorously evaluate novel primary or secondary prevention interventions that address prescription or illicit opioid overdose. Primary prevention approaches are expected to aim to prevent opioid misuse, abuse, and overdose before it occurs. Secondary prevention approaches are expected to focus on the more immediate responses to opioid overdose, such as emergency department services and linkage to treatment immediately following a nonfatal overdose. Clinical examinations of the treatment effectiveness for opioid use disorder are outside the scope of the objectives and will not be considered (e.g., studies that solely test the effectiveness of buprenorphine, methadone, or naltrexone).It is anticipated that funded applicants will collaborate and partner with community and/or governmental organizations from multiple sectors (e.g., health, social services, law enforcement, criminal justice) that can provide access to populations at highest risk for opioid misuse and overdose and provide access to critical data systems. Investigators must provide information in the application demonstrating that they have an established relationship with each partner and a written agreement describing each partner’s role in the proposed research.

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