DoD Peer Reviewed Cancer, Impact Award

Description

The FY19 PRCRP Impact Award supports hypothesis-driven, high-impact research. The Impact Award mechanism encourages applications with mature research projects that specifically focus on critical scientific or clinical cancer issues, which, if successfully addressed, have the potential to make a major impact on at least one of the FY19 PRCRP Topic Areas. Important factors under consideration will be continuity of research, clinical applicability, and leveraging of clinical samples and trials. Through the Impact Award, the PRCRP seeks to build foundations for finding cures in under-funded, under-studied, and/or lethal militarily relevant cancer or research areas. With the Impact Award, PRCRP offers the unique opportunity to find commonalities in research across multiple cancers that advance the broader cancer field and to address cancer funding disparities within the FY19 PRCRP Topic Areas. The Impact Award supports identifying scientific outcomes through rigorous, robust research that are translatable toward treatment and/or preventive strategies. Research proposed should aim to accelerate promising findings toward clinical applicability and leverage research results to maximize impact. The critical components of this award mechanism are: · Impact: The Impact Award is intended to support research that demonstrates the potential to have a major impact on an area of paramount importance in cancer. The proposed study should demonstrate how the research will transform cancer research toward improved patient care in at least one of the FY19 PRCRP Topic Areas and has potential near-term outcomes. The research should make a significant shift toward clinical applicability in at least one of the FY19 PRCRP Topic Areas. Research should challenge paradigms with respect to the endpoint of impact on patient care and outcomes. Proposed projects may include translational or clinical research, including clinical trials. The potential impact of the proposed research is expected to be near-term and it must be significant and go beyond an incremental advance. The applicant must articulate the potential impact the proposed work will have on cancer research and/or patient care. Impactful research will, if successful, accelerate the movement of promising ideas into clinical applications. The Impact Award is not intended for basic research. · Preliminary Data: The Impact Award is intended to support transformative investigations that leapfrog the cancer research field forward by utilizing previous research findings. Applications must include preliminary data to support feasibility of the study. Any unpublished, preliminary data provided should originate from the laboratory of the Principal Investigator (PI) or a member(s) of the research team. · Continuity of Research: The Impact Award is intended to support established projects that have moved beyond the realm of basic research and have the potential to result in a near-term impact in clinical research or the clinic. · Military Relevance: The proposed research must address at least one of the FY19 PRCRP Military Health Focus Areas. The proposed research must be relevant to active duty Service members, Veterans, and their beneficiaries. For more information, review the following websites: ○ PRCRP (https://cdmrp.army.mil/prcrp/default) ○ PRCRP Report to Congress (https://cdmrp.army.mil/prcrp/reports/reports) ○ Military Health System (MHS) (https://www.health.mil) ○ VA (https://www.va.gov/)

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