Closed · RFA-NS-21-005 · CFDA 93.853;93.866 · Discretionary

Small Vessel VCID Biomarker Validation Consortium Sites (U01)(Clinical Trials Not Allowed)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

up to $800K
Award range
Closed
Status
March 9, 2021
Close date
7
Expected awards

The verdict

Small Vessel VCID Biomarker Validation Consortium Sites (U01)(Clinical Trials Not Allowed) is a closed discretionary listing from National Institutes of Health that offered Up to $800,000 across 7 expected awards. Future funding cycles may be published under the same CFDA number.

up to $800K
award range
Closed
application status
7
expected awards
93.853;93.866
CFDA program

Opportunity snapshot. This Grants.gov announcement - Small Vessel VCID Biomarker Validation Consortium Sites (U01)(Clinical Trials Not Allowed) - is cataloged under number RFA-NS-21-005 and tied to CFDA assistance listing 93.853;93.866, posted by National Institutes of Health. Grants.gov currently shows the opportunity as closed, first posted on November 23, 2020. The funding category is Discretionary, delivered as a cooperative agreement.

Award economics. The award range on file is Up to $800,000. The agency has projected $8.4 million in total estimated funding for this announcement. It expects to issue 7 awards. If the agency funds the expected 7 awards from the $8.4 million estimated pool, the average award works out to roughly $1.2 million. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. This opportunity closed on March 9, 2021. Future funding cycles may be published under the same CFDA number, so monitoring the parent program page is the most reliable way to catch re-announcements. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.

Award Range

Up to $800,000

Close Date

March 9, 2021

Posted

November 23, 2020

Est. Total Funding

$8,400,000

Expected Awards

7

Instrument

Cooperative Agreement

Description

T?o invite applications to an open competition to be one of up to 7 supported sites in the next phase of the NINDS small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers consortium. The original consortium, established under RFA-NS-16-019 and RFA-NS-16-020, pursued initial stages of multi-site validation of 11 candidate imaging-based and fluid-based biomarkers. The primary objective of the next 5 years is to carry out comprehensive multi-site clinical validation of up to six of these 11 biomarkers to be selected by the NINDS in a process separate from this FOA. The focus will be validation in longitudinal studies of diverse all-comers populations that are typical in clinical settings in the United States. The network of sites will provide scientific expertise and experimental infrastructure to pursue these goals synergistically including with the Coordinating Center (RFA-NS-21-004). At the conclusion of clinical validation each biomarker will have a designated category and context of use as defined by the FDA and a finalized public protocol that describes all details needed to utilize the biomarker. The sites will drive the consortium scientifically and contribute administratively to comprehensive rigorous clinical validation of biomarkers for future clinical trials, including in large phase III trials, and for generating scientific breakthroughs in our understanding and treatment of VCID.

Eligibility

Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

NIH OER Webmaster FBOWebmaster@OD.NIH.GOV

Key Dates

Posted November 23, 2020
Close Date March 9, 2021
Archive Date April 14, 2021
Last Updated November 23, 2020

Frequently Asked Questions

What is this grant opportunity?
This is a federal funding opportunity titled "Small Vessel VCID Biomarker Validation Consortium Sites (U01)(Clinical Trials Not Allowed)", offered by National Institutes of Health. It is associated with CFDA program 93.853;93.866. T?o invite applications to an open competition to be one of up to 7 supported sites in the next phase of the NINDS small vessel vascular contributions to cognitive impairment and dementia (VCID) bioma...
Is this opportunity still open?
No, this opportunity is closed. It closed on March 9, 2021. Check the parent program page for future funding cycles.
How much funding is available?
The award range for this opportunity is Up to $800,000. Total estimated funding: $8,400,000. Expected number of awards: 7.
How do I apply?
Applications for federal grant opportunities are typically submitted through Grants.gov. Visit the official listing at grants.gov for application instructions, required documents, and submission deadlines.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants