CDMRP PRMRP Technology/Therapeutic Development Award

Description

The PRMRP Technology/Therapeutic Development Award is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, in at least one of the Congressionally directed FY21 PRMRP Topic Areas. Products in development should be responsive to the healthcare needs of military Service Members, Veterans, and/or beneficiaries.The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. (A “knowledge product” is a non-materiel product that addresses an identified need in a Topic Area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.) The Principal Investigator (PI) must provide a transition plan (including potential funding and resources, see Attachment 8) showing how the product will progress to the next level of development (e.g., clinical trials, delivery to the military or civilian market) after the completion of the PRMRP award. PIs are encouraged to develop relationships with industry and/or other funding agencies to facilitate moving the product into the next phase of development.Proof of concept demonstrating the potential utility of the proposed product, or a prototype/ preliminary version of the proposed product, should already be established. Applications must include relevant data that support the rationale for the proposed study. These data may be unpublished and/or from the published literature. Investigators seeking to identify a product or demonstrate initial proof of concept should consider submitting to the FY21 PRMRP Investigator-Initiated Research Award (Funding Opportunity Number W81XWH-21-PRMRP-IIRA) or the FY21 PRMRP Discovery Award (Funding Opportunity Number W81XWH-21-PRMRP-DA), as appropriate.Research proposed under this award mechanism may be at different stages of idea and research development. Two different funding levels, based on the scope of the research, are available under this program announcement. The applicant must select the funding level that is most appropriate for the research proposed.

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