Closed · PAS-21-215 · CFDA 93.242 · Discretionary
Identification of Positive Valence System Related Targets for Novel Suicide Prevention Approaches (R21 Clinical Trial Optional)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- Varies
- Award range
- Closed
- Status
- October 16, 2021
- Close date
- -
- Expected awards
The verdict
Identification of Positive Valence System Related Targets for Novel Suicide Prevention Approaches (R21 Clinical Trial Optional) is a closed discretionary listing from National Institutes of Health that offered Varies by applicant. Future funding cycles may be published under the same CFDA number. PlainGrants indexes 12,419 other opportunities from National Institutes of Health.
- Varies
- award range
- Closed
- application status
- 93.242
- CFDA program
- 12,419
- other opportunities from National Institutes of Health
Archived opportunity record
Identification of Positive Valence System Rel… is closed (last close October 16, 2021). The parent program page for CFDA 93.242 is the reliable place to catch re-announcements. National Institutes of Health still indexes 12,419 other opportunities here.
According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.
Deadline tracker
Application window closed
Closed October 16, 2021
Instrument
Grant
Description
The primary objective of this FOA is to solicit research projects with the aim of elucidating the role of positive affect and related processes in suicidal individuals and evaluating modifiable behavioral and neural targets. Specifically, studies should include clinical populations with high risk of suicide, suicide attempters or acutely suicidal individuals, and may also include non-suicidal patients, high risk individuals in an absence of diagnosis, or healthy control groups. Projects across developmental spectrum are encouraged. Research projects should aim to 1) specify a construct of interest either in terms of research domain criteria: positive valence system (RDoC PVS), or a symptom relevant construct, such as an anhedonia/ anhedonia subtype, cognitive process such as present/future reward decision making, generating reasons for living in the context of anticipation of positive experiences, etc. 2) demonstrate that measures of the construct are reliable and reproducible and engage brain subsystem relevant to positive affect, and/or 3) show active modification of targeted brain system and behavioral measures of the construct through behavioral training or other means such as use of non-invasive neuromodulation, pharmacological or psychosocial therapeutic probes. Behavioral tasks used may include both novel and established tasks within the RDoC positive valence domain (e.g. reward sensitivity, reward valuation, and reward learning) and/or tasks probing components and subconstructs of hedonic and related processes. Use of measures of the dynamic changes in PA is strongly encouraged to further establish co-occurrence with other risk factors and suicidality.
Wide-open applicant board · 15 Grants.gov doors
Identification of Positive Valence System Rel… prints 15 distinct Grants.gov eligibility doors (State governments; County governments; City or township governments; Special district governments; +11 more). Filter fit before reading award size as demand — most applicant classes appear on the row. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity code maps to Health (HL). This eligibility-code string dominates the National Institutes of Health book (9,741 peers, 78% of 12,420).
- Code 00
- State governments
- Code 01
- County governments
- Code 02
- City or township governments
- Code 04
- Special district governments
- Code 05
- Independent school districts
- Code 06
- Public / state-controlled institutions of higher education
- Code 07
- Federally recognized tribal governments
- Code 08
- Public / Indian housing authorities
- Code 11
- Native American tribal organizations (other than Federally recognized tribal governments)
- Code 12
- Nonprofits with 501(c)(3) status (other than IHEs)
- Code 13
- Nonprofits without 501(c)(3) status (other than IHEs)
- Code 20
- Private institutions of higher education
- Code 22
- For-profit organizations other than small businesses
- Code 23
- Small businesses
- Code 25
- Others (see official listing text)
Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Parent Grant Program
Mental Health Research Grants
National Institutes of Health
Agency Contact
NIH OER Webmaster grantsinfo@nih.gov
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What to do next
Identification of Positive Valence System Rel… is closed; use the parent program and agency catalog for the next funding cycle.
- Parent CFDA 93.242 may publish future NOFOs under the same assistance listing. Open program
- Mental Health Research Grants indexes 185 Grants.gov listings in this extract. Program profile
- National Institutes of Health lists 12,419 other indexed opportunities on PlainGrants. Agency catalog
Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.
Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
| Publisher | PlainGrants |
| Sources | the SAM.gov Assistance Listings and Grants.gov |