Closed · EPA-G2022-STAR-A2 · CFDA 66.509 · Discretionary

Early Career: Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures

Federal grant opportunity posted by Environmental Protection Agency, cataloged on Grants.gov.

up to $600K
Award range
Closed
Status
December 8, 2021
Close date
2
Expected awards

The verdict

Early Career: Development of Innovative Approaches to Assess the Toxicity of Chemical Mixtures is a closed discretionary listing from Environmental Protection Agency that offered Up to $600,000 across 2 expected awards. Future funding cycles may be published under the same CFDA number. PlainGrants indexes 1,487 other opportunities from Environmental Protection Agency.

up to $600K
award range
Closed
application status
2
expected awards
66.509
CFDA program

Archived opportunity record

Early Career: Development of Innovative Appro… is closed (last close December 8, 2021). The parent program page for CFDA 66.509 is the reliable place to catch re-announcements. Environmental Protection Agency still indexes 1,487 other opportunities here.

According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.

Deadline tracker

Application window closed

Closed December 8, 2021

Posted Oct 8 Closes Dec 8

Est. Total Funding

$4,200,000

Expected Awards

2

Instrument

Grant

Description

This Request for Applications (RFA) solicits research focused on the development and evaluation of innovative methods and approaches to inform human health risk assessment of environmental chemical mixtures. Because most of the human chemical body burden involves concurrent or sequential exposures to mixtures of chemicals, methods to make better-informed, timelier evaluations of chemical mixtures of known, or partially-known, composition have long been needed. A challenge in conducting mixtures assessment is the lack of useful hazard and dose response data and other information on chemical mixtures. Potential chemical mixtures exposures of public health concern typically encountered in environmental media may include classes or subclasses of compounds (for example, per- and polyfluoroalkyl substances [PFAS], phthalates, polycyclic aromatic hydrocarbons [PAHs], disinfection by-products [DBPs]), or any other well-characterized mixtures. Applications are being sought that propose approaches and strategies that integrate in vitro, in silico, and/or non-mammalian in vivo methods that can contribute to decision-making science associated with toxicity evaluation and human health assessment of chemical mixtures.

Catch-all / unrestricted eligibility mark · EPA-G2022-STAR-A2

Grants.gov marks Early Career: Development of Innovative Appro… with a catch-all / unrestricted eligibility code (Others (see official listing text)). Read the official announcement text for the real applicant filter — the code alone is not a door list. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity code maps to Environment (ENV). This eligibility-code string dominates the Environmental Protection Agency book (1,239 peers, 83% of 1,488).

Code 25
Others (see official listing text)

Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Parent Grant Program

CFDA 66.509

Science to Achieve Results (STAR)

U.S. Environmental Protection Agency

View program →

Agency Contact

Hayley Aja, Technical Contact, Phone: 202-564-6427

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What to do next

Early Career: Development of Innovative Appro… is closed; use the parent program and agency catalog for the next funding cycle.

  • Parent CFDA 66.509 may publish future NOFOs under the same assistance listing. Open program
  • Science to Achieve Results (STAR) indexes 3 Grants.gov listings in this extract. Program profile
  • Environmental Protection Agency lists 1,487 other indexed opportunities on PlainGrants. Agency catalog

Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants