Open · RFA-DA-25-060 · CFDA 93.279 · Discretionary

High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

up to $1.5M
Award range
Open
Status
175d
Days left
-
Expected awards

The verdict

High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering Up to $1,500,000. Applications close in 175 days. PlainGrants indexes 12,419 other opportunities from National Institutes of Health.

up to $1.5M
award range
Open
175 days left
93.279
CFDA program
12,419
other opportunities from National Institutes of Health

Open desk with published close date

High Priority HIV and Substance Use Research remains open until March 5, 2027 (175 days out). Large award band (Up to $1,500,000) without a cost-share requirement. Parent CFDA 93.279 may carry future cycles if this NOFO closes unfunded.

According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.

Deadline tracker

175 days left to apply

Posted Jan 17 → closes Mar 5, 2027

Posted Jan 17 Closes Mar 5

Instrument

Grant

Description

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Wide-open applicant board · 15 Grants.gov doors

High Priority HIV and Substance Use Research prints 15 distinct Grants.gov eligibility doors (State governments; County governments; City or township governments; Special district governments; +11 more). Filter fit before reading award size as demand — most applicant classes appear on the row. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity codes span Education · Health (ED;HL). This eligibility-code string dominates the National Institutes of Health book (9,741 peers, 78% of 12,420).

Code 00
State governments
Code 01
County governments
Code 02
City or township governments
Code 04
Special district governments
Code 05
Independent school districts
Code 06
Public / state-controlled institutions of higher education
Code 07
Federally recognized tribal governments
Code 08
Public / Indian housing authorities
Code 11
Native American tribal organizations (other than Federally recognized tribal governments)
Code 12
Nonprofits with 501(c)(3) status (other than IHEs)
Code 13
Nonprofits without 501(c)(3) status (other than IHEs)
Code 20
Private institutions of higher education
Code 22
For-profit organizations other than small businesses
Code 23
Small businesses
Code 25
Others (see official listing text)

Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

NIH Grants Information grantsinfo@nih.gov

What to do next

High Priority HIV and Substance Use Research is open with Up to $1,500,000 awards and 175 days left on the clock.

  • Submit through Grants.gov (RFA-DA-25-060) - verify SAM.gov registration and the current NOFO before drafting. Official listing
  • Drug Abuse Research Programs indexes 170 Grants.gov listings in this extract. Program profile
  • National Institutes of Health lists 12,419 other indexed opportunities on PlainGrants. Agency catalog

Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants