Closed · RFA-AG-25-019 · CFDA 93.866 · Discretionary
The Impact of Stressors on the Biological Mechanisms of Aging and Other Aging-Associated Outcomes in Experimental Model Systems (R61/R33 Clinical Trial Not allowed)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- Varies
- Award range
- Closed
- Status
- November 7, 2024
- Close date
- -
- Expected awards
The verdict
The Impact of Stressors on the Biological Mechanisms of Aging and Other Aging-Associated Outcomes in Experimental Model Systems (R61/R33 Clinical Trial Not allowed) is a closed discretionary listing from National Institutes of Health that offered Varies by applicant. Future funding cycles may be published under the same CFDA number. PlainGrants indexes 12,419 other opportunities from National Institutes of Health.
- Varies
- award range
- Closed
- application status
- 93.866
- CFDA program
- 12,419
- other opportunities from National Institutes of Health
Archived opportunity record
The Impact of Stressors on the Biological Mec… is closed (last close November 7, 2024). Check the agency catalog for replacement NOFOs. National Institutes of Health still indexes 12,419 other opportunities here.
According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.
Deadline tracker
Application window closed
Closed November 7, 2024
Instrument
Grant
Description
Stress is a natural and universal part of life. However, studies that use model systems to investigate the biological mechanisms underlying the aging process (i.e., the hallmarks of aging) and interventions to retard it do not usually integrate exposures to stressors, which limits the translatability of their findings. The overarching objective of this notice of funding opportunity (NOFO) is to invite applications proposing research that incorporates exposures to a stressor(s) during the post-development period (adulthood) into studies of aging processes. Research proposed in the initial, exploratory (R61) phase will seek to determine whether exposure to a stressor(s) (e.g., physical, social, and/or environmental stressors of well-defined duration, intensity, and timing) during adulthood result in measurable changes in one or more of the hallmarks of aging. The second, developmental (R33) phase will then expand upon findings yielded in the R61 phase to determine the impacts of the stressor(s) on lifespan, healthspan, resilience, and/or interactions with other input variables such as genotype, diet, interventions, etc. Applicants can propose to employ in vitro systems; laboratory animals; or well-characterized wild, captive, free-ranging, or domesticated animal populations. Funded projects will receive up to two years of R61 support and may also receive up to three years of R33 support (contingent upon NIAs determination of the success in achieving R61 milestones, NIA priorities, and availability of funds).
Wide-open applicant board · 15 Grants.gov doors
The Impact of Stressors on the Biological Mec… prints 15 distinct Grants.gov eligibility doors (State governments; County governments; City or township governments; Special district governments; +11 more). Filter fit before reading award size as demand — most applicant classes appear on the row. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity code maps to Health (HL). This eligibility-code string dominates the National Institutes of Health book (9,741 peers, 78% of 12,420).
- Code 00
- State governments
- Code 01
- County governments
- Code 02
- City or township governments
- Code 04
- Special district governments
- Code 05
- Independent school districts
- Code 06
- Public / state-controlled institutions of higher education
- Code 07
- Federally recognized tribal governments
- Code 08
- Public / Indian housing authorities
- Code 11
- Native American tribal organizations (other than Federally recognized tribal governments)
- Code 12
- Nonprofits with 501(c)(3) status (other than IHEs)
- Code 13
- Nonprofits without 501(c)(3) status (other than IHEs)
- Code 20
- Private institutions of higher education
- Code 22
- For-profit organizations other than small businesses
- Code 23
- Small businesses
- Code 25
- Others (see official listing text)
Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
NIH Grants Information grantsinfo@nih.gov
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What to do next
The Impact of Stressors on the Biological Mec… is closed; use the parent program and agency catalog for the next funding cycle.
- Browse open federal opportunities in the same category when this listing is closed. Open opportunities
- Look up CFDA 93.866 across all indexed listings before you commit to this opportunity alone. Eligibility finder
- National Institutes of Health lists 12,419 other indexed opportunities on PlainGrants. Agency catalog
Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.
Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
| Publisher | PlainGrants |
| Sources | the SAM.gov Assistance Listings and Grants.gov |