Open · RFA-AT-25-003 · CFDA 93.121;93.213;93.273;93.846;93.853;93.865;93.866 · Discretionary

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

up to $375K
Award range
Open
Status
29d
Days left
-
Expected awards

The verdict

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering Up to $375,000. Applications close in 29 days. PlainGrants indexes 12,419 other opportunities from National Institutes of Health.

up to $375K
award range
Open
29 days left
93.121;93.213;93.273;93.846;93.853;93.865;93.866
CFDA program
12,419
other opportunities from National Institutes of Health

Open desk with published close date

HEAL Initiative: Pain Research Enhancement Pr… remains open until November 23, 2026 (29 days out). Award range Up to $375,000 without a cost-share requirement.

According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.

Deadline tracker

29 days left to apply

Posted Jan 8 → closes Nov 23, 2026

Posted Jan 8 Closes Nov 23

Instrument

Grant

Description

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

Multi-door applicant board · 3 Grants.gov types

Grants.gov prints 3 distinct applicant types for HEAL Initiative: Pain Research Enhancement Pr… (Public / state-controlled institutions of higher education; Private institutions of higher education; Others (see official listing text)). Filter fit against the official announcement before drafting. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity codes span Health · Income Security and Social Services (HL;ISS). Only 256 other National Institutes of Health listings share this exact eligibility-code string (2% of 12,420).

Code 06
Public / state-controlled institutions of higher education
Code 20
Private institutions of higher education
Code 25
Others (see official listing text)

Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

NIH Grants Information grantsinfo@nih.gov

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What to do next

HEAL Initiative: Pain Research Enhancement Pr… is open with Up to $375,000 awards and 29 days left on the clock.

  • Submit through Grants.gov (RFA-AT-25-003) - verify SAM.gov registration and the current NOFO before drafting. Official listing
  • Look up CFDA 93.121;93.213;93.273;93.846;93.853;93.865;93.866 across all indexed listings before you commit to this opportunity alone. Eligibility finder
  • National Institutes of Health lists 12,419 other indexed opportunities on PlainGrants. Agency catalog

Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants