Open · RFA-HG-27-013 · CFDA 93.172 · Discretionary
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- $3-$500K
- Award range
- Open
- Status
- 77d
- Days left
- 10
- Expected awards
The verdict
GREGoRi Innovation Projects (U01 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering $3 -- $500,000 across 10 expected awards. Applications close in 77 days.
- $3-$500K
- award range
- Open
- 77 days left
- 10
- expected awards
- 93.172
- CFDA program
Opportunity snapshot. This Grants.gov announcement - GREGoRi Innovation Projects (U01 Clinical Trial Optional) - is cataloged under number RFA-HG-27-013 and tied to CFDA assistance listing 93.172, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on June 18, 2026. The funding category is Discretionary, delivered as a cooperative agreement.
Award economics. The award range on file is $3 -- $500,000. The agency has projected $7.5 million in total estimated funding for this announcement. It expects to issue 10 awards. If the agency funds the expected 10 awards from the $7.5 million estimated pool, the average award works out to roughly $750,000. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. Applications close on October 30, 2026 - roughly 77 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
$3 -- $500,000
Close Date
October 30, 2026
Posted
June 18, 2026
Est. Total Funding
$7,500,000
Expected Awards
10
Instrument
Cooperative Agreement
Description
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Eligibility
Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
GREGoRi Program Team nhgri-gregor@mail.nih.gov
Key Dates
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Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
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| Publisher | PlainGrants |
| Sources | the SAM.gov Assistance Listings and Grants.gov |