Open · RFA-CA-27-021 · CFDA 93.393;93.394;93.395;93.396;93.399 · Discretionary
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- $50K-$600K
- Award range
- Open
- Status
- 67d
- Days left
- 2
- Expected awards
The verdict
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering $50,000 -- $600,000 across 2 expected awards. Applications close in 67 days.
- $50K-$600K
- award range
- Open
- 67 days left
- 2
- expected awards
- 93.393;93.394;93.395;93.396;93.399
- CFDA program
Opportunity snapshot. This Grants.gov announcement - Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) - is cataloged under number RFA-CA-27-021 and tied to CFDA assistance listing 93.393;93.394;93.395;93.396;93.399, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on May 21, 2026. The funding category is Discretionary, delivered as a cooperative agreement.
Award economics. The award range on file is $50,000 -- $600,000. The agency has projected $1.8 million in total estimated funding for this announcement. It expects to issue 2 awards. If the agency funds the expected 2 awards from the $1.8 million estimated pool, the average award works out to roughly $900,000. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. Applications close on October 19, 2026 - roughly 67 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
$50,000 -- $600,000
Close Date
October 19, 2026
Posted
May 21, 2026
Est. Total Funding
$1,800,000
Expected Awards
2
Instrument
Cooperative Agreement
Description
This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer researchRobust plans for supporting the end-user community including documentation, training, and other outreach activitiesClear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports
Eligibility
Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov
Key Dates
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Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
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| Sources | the SAM.gov Assistance Listings and Grants.gov |