Open · RFA-CA-27-020 · CFDA 93.393;93.394;93.395;93.396;93.399 · Discretionary

Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

$50K-$600K
Award range
Open
Status
67d
Days left
3
Expected awards

The verdict

Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering $50,000 -- $600,000 across 3 expected awards. Applications close in 67 days.

$50K-$600K
award range
Open
67 days left
3
expected awards
93.393;93.394;93.395;93.396;93.399
CFDA program

Opportunity snapshot. This Grants.gov announcement - Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) - is cataloged under number RFA-CA-27-020 and tied to CFDA assistance listing 93.393;93.394;93.395;93.396;93.399, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on May 21, 2026. The funding category is Discretionary, delivered as a cooperative agreement.

Award economics. The award range on file is $50,000 -- $600,000. The agency has projected $2.6 million in total estimated funding for this announcement. It expects to issue 3 awards. If the agency funds the expected 3 awards from the $2.6 million estimated pool, the average award works out to roughly $867,000. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. Applications close on October 19, 2026 - roughly 67 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.

Award Range

$50,000 -- $600,000

Close Date

October 19, 2026

Posted

May 21, 2026

Est. Total Funding

$2,600,000

Expected Awards

3

Instrument

Cooperative Agreement

Description

This Notice of Funding Opportunity (NOFO) invites applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and interpretation of data across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on advancing emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. To be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving cancer research projects as well as the broader user community throughout the development process must be included.This NOFO invites applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in general;Offers clear advantages over competing technologies in the targeted cancer research domain;Provides compelling plans and processes for supporting and engaging end users to evaluate and apply the tool or resource;Provides plans for advancing use of the tool or resource by the targeted community through collaboration, outreach, and training;Provides a realistic timeline and milestones for technology development.

Eligibility

Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov

Key Dates

Posted May 21, 2026
Close Date October 19, 2026
Archive Date December 19, 2026
Last Updated May 21, 2026

Frequently Asked Questions

What is this grant opportunity?
This is a federal funding opportunity titled "Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)", offered by National Institutes of Health. It is associated with CFDA program 93.393;93.394;93.395;93.396;93.399. This Notice of Funding Opportunity (NOFO) invites applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and in...
Is this opportunity still open?
Yes, this opportunity is currently open for applications. The closing date is October 19, 2026.
How much funding is available?
The award range for this opportunity is $50,000 -- $600,000. Total estimated funding: $2,600,000. Expected number of awards: 3.
How do I apply?
Applications for federal grant opportunities are typically submitted through Grants.gov. Visit the official listing at grants.gov for application instructions, required documents, and submission deadlines.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants