Open · RFA-CA-27-019 · CFDA 93.393;93.394;93.395;93.396;93.399 · Discretionary
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- $50K-$300K
- Award range
- Open
- Status
- 432d
- Days left
- 5
- Expected awards
The verdict
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering $50,000 -- $300,000 across 5 expected awards. Applications close in 432 days.
- $50K-$300K
- award range
- Open
- 432 days left
- 5
- expected awards
- 93.393;93.394;93.395;93.396;93.399
- CFDA program
Opportunity snapshot. This Grants.gov announcement - Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) - is cataloged under number RFA-CA-27-019 and tied to CFDA assistance listing 93.393;93.394;93.395;93.396;93.399, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on May 21, 2026. The funding category is Discretionary, delivered as a cooperative agreement.
Award economics. The award range on file is $50,000 -- $300,000. The agency has projected $2.4 million in total estimated funding for this announcement. It expects to issue 5 awards. If the agency funds the expected 5 awards from the $2.4 million estimated pool, the average award works out to roughly $480,000. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. Applications close on October 19, 2027 - roughly 432 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
$50,000 -- $300,000
Close Date
October 19, 2027
Posted
May 21, 2026
Est. Total Funding
$2,400,000
Expected Awards
5
Instrument
Cooperative Agreement
Description
This Notice of Funding Opportunity (NOFO) solicits applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on early-stage development from prototyping to initial dissemination. Early-stage development is defined for the purpose of this NOFO as initial tool development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving research projects and other users throughout the development process must be included.This NOFO encourages applications that involve the development of new, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in generalNovel informatics capabilities for the targeted cancer research domainCompelling plans and processes for engaging end users to evaluate and apply the tool or resourceA realistic timeline and milestones for technology development
Eligibility
Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov
Key Dates
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Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
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| Sources | the SAM.gov Assistance Listings and Grants.gov |