Open · RFA-FD-25-017 · CFDA 93.103 · Discretionary
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
Federal grant opportunity posted by Food and Drug Administration, cataloged on Grants.gov.
- up to $600K
- Award range
- Open
- Status
- 515d
- Days left
- -
- Expected awards
The verdict
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional) is an open discretionary opportunity from Food and Drug Administration, offering Up to $600,000. Applications close in 515 days. PlainGrants indexes 481 other opportunities from Food and Drug Administration.
- up to $600K
- award range
- Open
- 515 days left
- 93.103
- CFDA program
- 481
- other opportunities from Food and Drug Administration
Open desk with published close date
Reissue of RFA-FD-22-001 remains open until February 8, 2028 (515 days out). Award range Up to $600,000 without a cost-share requirement. Parent CFDA 93.103 may carry future cycles if this NOFO closes unfunded.
According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.
Deadline tracker
515 days left to apply
Posted Jul 11 → closes Feb 8, 2028
Instrument
Grant
Description
The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and facilitate rare disease product development.
Catch-all / unrestricted eligibility mark · RFA-FD-25-017
Grants.gov marks Reissue of RFA-FD-22-001 with a catch-all / unrestricted eligibility code (Others (see official listing text)). Read the official announcement text for the real applicant filter — the code alone is not a door list. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity codes span Agriculture · Consumer Protection · Food and Nutrition (AG;CP;FN). 119 other Food and Drug Administration listings share this eligibility-code string (25% of 482).
- Code 25
- Others (see official listing text)
Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Parent Grant Program
Food and Drug Administration Research
U.S. Department of Health and Human Services
Agency Contact
Kimberly Pendleton Chief Grants Management Officer
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What to do next
Reissue of RFA-FD-22-001 is open with Up to $600,000 awards and 515 days left on the clock.
- Submit through Grants.gov (RFA-FD-25-017) - verify SAM.gov registration and the current NOFO before drafting. Official listing
- Food and Drug Administration Research indexes 42 Grants.gov listings in this extract. Program profile
- Food and Drug Administration lists 481 other indexed opportunities on PlainGrants. Agency catalog
Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.
Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
| Publisher | PlainGrants |
| Sources | the SAM.gov Assistance Listings and Grants.gov |