Open · RFA-OD-27-004 · CFDA 93.121;93.173;93.233;93.242;93.310;93.350;93.351;93.395;93.837;93.838;93.839;93.840;93.846;93.847;93.855;93.865;93.866;93.867;93.879 · Discretionary

INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

up to $500K
Award range
Open
Status
600d
Days left
4
Expected awards

The verdict

INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) is an open discretionary opportunity from National Institutes of Health, offering Up to $500,000 across 4 expected awards. Applications close in 600 days. PlainGrants indexes 12,419 other opportunities from National Institutes of Health.

up to $500K
award range
Open
600 days left
4
expected awards
93.121;93.173;93.233;93.242;93.310;93.350;93.351;93.395;93.837;93.838;93.839;93.840;93.846;93.847;93.855;93.865;93.866;93.867;93.879
CFDA program

Open desk with published close date

INCLUDE Project: Transformative Research Awar… remains open until June 15, 2028 (600 days out). Award range Up to $500,000 without a cost-share requirement.

According to Grants.gov (extract vintage 2026-08-10), this record reflects the officially published listing. See methodology.

Deadline tracker

600 days left to apply

Posted May 12 → closes Jun 15, 2028

Posted May 12 Closes Jun 15

Est. Total Funding

$3,000,000

Expected Awards

4

Instrument

Grant

Description

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

Wide-open applicant board · 15 Grants.gov doors

INCLUDE Project: Transformative Research Awar… prints 15 distinct Grants.gov eligibility doors (State governments; County governments; City or township governments; Special district governments; +11 more). Filter fit before reading award size as demand — most applicant classes appear on the row. The extract does not mark applicant cost-sharing as required. Instrument: Grant. Funding-activity code maps to Health (HL). This eligibility-code string dominates the National Institutes of Health book (9,741 peers, 78% of 12,420).

Code 00
State governments
Code 01
County governments
Code 02
City or township governments
Code 04
Special district governments
Code 05
Independent school districts
Code 06
Public / state-controlled institutions of higher education
Code 07
Federally recognized tribal governments
Code 08
Public / Indian housing authorities
Code 11
Native American tribal organizations (other than Federally recognized tribal governments)
Code 12
Nonprofits with 501(c)(3) status (other than IHEs)
Code 13
Nonprofits without 501(c)(3) status (other than IHEs)
Code 20
Private institutions of higher education
Code 22
For-profit organizations other than small businesses
Code 23
Small businesses
Code 25
Others (see official listing text)

Codes are Grants.gov eligibility category values from the extract vintage 2026-08-10. Confirm the full eligibility statement on the official listing or the Grants.gov eligibility reference.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

The INCLUDE Project DownSyndromeINCLUDE@mail.nih.gov

What to do next

INCLUDE Project: Transformative Research Awar… is open with Up to $500,000 awards and 600 days left on the clock.

  • Submit through Grants.gov (RFA-OD-27-004) - verify SAM.gov registration and the current NOFO before drafting. Official listing
  • Look up CFDA 93.121;93.173;93.233;93.242;93.310;93.350;93.351;93.395;93.837;93.838;93.839;93.840;93.846;93.847;93.855;93.865;93.866;93.867;93.879 across all indexed listings before you commit to this opportunity alone. Eligibility finder
  • National Institutes of Health lists 12,419 other indexed opportunities on PlainGrants. Agency catalog

Opportunity deadlines and eligibility change on Grants.gov; PlainGrants mirrors the extract and is not the submission system.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants