Open · RFA-CA-27-012 · CFDA 93.396 · Discretionary
Metastasis Research Network (U54 Clinical Trial Not Allowed)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- up to $1.3M
- Award range
- Open
- Status
- 42d
- Days left
- 4
- Expected awards
The verdict
Metastasis Research Network (U54 Clinical Trial Not Allowed) is an open discretionary opportunity from National Institutes of Health, offering Up to $1,300,000 across 4 expected awards. Applications close in 42 days.
- up to $1.3M
- award range
- Open
- 42 days left
- 4
- expected awards
- 93.396
- CFDA program
Opportunity snapshot. This Grants.gov announcement - Metastasis Research Network (U54 Clinical Trial Not Allowed) - is cataloged under number RFA-CA-27-012 and tied to CFDA assistance listing 93.396, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on June 4, 2026. The funding category is Discretionary, delivered as a cooperative agreement.
Award economics. The award range on file is Up to $1,300,000. The agency has projected $6.8 million in total estimated funding for this announcement. It expects to issue 4 awards. If the agency funds the expected 4 awards from the $6.8 million estimated pool, the average award works out to roughly $1.7 million. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. Applications close on September 25, 2026 - roughly 42 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
Up to $1,300,000
Close Date
September 25, 2026
Posted
June 4, 2026
Est. Total Funding
$6,800,000
Expected Awards
4
Instrument
Cooperative Agreement
Description
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements in the metastatic process such as early dissemination, cellular, soluble and/or physical microenvironment crosstalk, dormancy, or mechanisms of responses by metastatic cells to therapies. Studies on all types of cancer are welcome, including rare and pediatric metastatic cancers.Research proposed by MetNet Centers is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.
Eligibility
Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
NCI MetNet Research Program NCIMetNet@mail.nih.gov
Key Dates
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Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
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| Sources | the SAM.gov Assistance Listings and Grants.gov |