Open · RFA-RM-27-001 · CFDA 93.310 · Discretionary
NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)
Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.
- $700K-$700K
- Award range
- Open
- Status
- 26d
- Days left
- 8
- Expected awards
The verdict
NIH Director’s Pioneer Award (DP1 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering $700,000 -- $700,000 across 8 expected awards. Applications close in 26 days.
- $700K-$700K
- award range
- Open
- 26 days left
- 8
- expected awards
- 93.310
- CFDA program
Opportunity snapshot. This Grants.gov announcement - NIH Director’s Pioneer Award (DP1 Clinical Trial Optional) - is cataloged under number RFA-RM-27-001 and tied to CFDA assistance listing 93.310, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on June 29, 2026. The funding category is Discretionary, delivered as a grant.
Award economics. The award range on file is $700,000 -- $700,000. The agency has projected $8.0 million in total estimated funding for this announcement. It expects to issue 8 awards. If the agency funds the expected 8 awards from the $8.0 million estimated pool, the average award works out to roughly $1.0 million. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. Applications close on September 9, 2026 - roughly 26 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
$700,000 -- $700,000
Close Date
September 9, 2026
Posted
June 29, 2026
Est. Total Funding
$8,000,000
Expected Awards
8
Instrument
Grant
Description
The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.
Eligibility
Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
NIH Director's Pioneer Award Program PioneerAwards@mail.nih.gov
Key Dates
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Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.
Read our methodology - how this data is sourced, computed, and verified.
Related
| Publisher | PlainGrants |
| Sources | the SAM.gov Assistance Listings and Grants.gov |