Substance Abuse and Mental Health Services (SAMHSA)

Program overview. CFDA 93.243 — Substance Abuse and Mental Health Services (SAMHSA) — is a federal assistance listing in the Health category, administered by U.S. Department of Health and Human Services (HHS). The typical award range cataloged on SAM.gov is $200,000 to $5.0 million. The program is currently active in the SAM.gov Assistance Listings database. Eligible applicants include State or Local Government, Nonprofit Organization.

Funding opportunities. PlainGrants has indexed 20 Grants.gov opportunity announcements tied to CFDA 93.243. Of those, 1 is currently open for applications and 19 have closed. The next closing date is April 20, 2026. The largest award ceiling seen across these announcements is $231.5 million. Agencies have projected roughly $480.6 million in total estimated funding across the indexed announcements for this CFDA number. Individual Notice of Funding Opportunity documents on Grants.gov carry the exact deadlines, required forms, and submission instructions.

Next steps. Before applying for CFDA 93.243, confirm your organization has an active SAM.gov registration and a Unique Entity ID (UEI) — these are mandatory for every federal funding instrument. Read the current Notice of Funding Opportunity end-to-end, paying close attention to the cost-share or matching requirement, the evaluation criteria, and the narrative page limits. Health-category grants routinely require Institutional Review Board (IRB) approval for any research involving human subjects and may require Single Project Assurance registration. For structural help, the guides linked below cover SAM.gov setup, NOFO interpretation, and common rejection reasons.