Closed · HR001124S0032 · CFDA 12.910 · Discretionary
Broad-Spectrum Antagonists For Editors (B-SAFE)
Federal grant opportunity posted by DARPA - Biological Technologies Office, cataloged on Grants.gov.
- Varies
- Award range
- Closed
- Status
- August 12, 2024
- Close date
- -
- Expected awards
The verdict
Broad-Spectrum Antagonists For Editors (B-SAFE) is a closed discretionary listing from DARPA - Biological Technologies Office that offered Varies by applicant. Future funding cycles may be published under the same CFDA number.
- Varies
- award range
- Closed
- application status
- 12.910
- CFDA program
Opportunity snapshot. This Grants.gov announcement - Broad-Spectrum Antagonists For Editors (B-SAFE) - is cataloged under number HR001124S0032 and tied to CFDA assistance listing 12.910, posted by DARPA - Biological Technologies Office. Grants.gov currently shows the opportunity as closed, first posted on June 14, 2024 and last updated on July 29, 2024. The funding category is Discretionary, delivered as a procurement contract.
Award economics. The award range on file is Varies by applicant. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. This opportunity closed on August 12, 2024. Future funding cycles may be published under the same CFDA number, so monitoring the parent program page is the most reliable way to catch re-announcements. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
Varies by applicant
Close Date
August 12, 2024
See Full Announcement for details.
Posted
June 14, 2024
Instrument
Procurement Contract
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to identify and optimize novel molecules that exhibit inhibitory effects on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated proteins (CRISPR-Cas) gene editing processes. The Broad-Spectrum Antagonists for Editors (B-SAFE) program is explicitly seeking transformative approaches enabling the discovery or design of novel inhibitors of gene editing technologies with enhanced activity, utility, and breadth of coverage. Novel inhibitor activity will be assessed in vitro over the course of the program and a subset of top performing molecules will be selected for scale-up at quantities sufficient for testing and evaluation by Department of Defense (DoD) stakeholders. In concert, DARPA is interested in exploring methods to rapidly discover inhibitor molecules for novel gene editing technologies beyond CRISPR-Cas systems to keep pace with the rapidly advancing field and promote the safe, controlled use of these technologies. Research that generates incremental improvements to the existing state-of-the-art are specifically excluded.
Eligibility
Grants.gov lists this opportunity under eligibility category code 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Agency Contact
BAA Coordinator BSAFE@darpa.mil
Key Dates
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| Sources | the SAM.gov Assistance Listings and Grants.gov |