Open PAS-25-161 CFDA 93.273 Discretionary

HIV Prevention and Alcohol (R34 Clinical Trials Optional)

Posted by National Institutes of Health

Opportunity snapshot. This Grants.gov announcement — HIV Prevention and Alcohol (R34 Clinical Trials Optional) — is cataloged under number PAS-25-161 and tied to CFDA assistance listing 93.273, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on November 25, 2024. The funding category is Discretionary, delivered as a grant.

Award economics. The award range on file is Up to $450,000. The agency has projected $225,000 in total estimated funding for this announcement. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. Applications close on May 7, 2026. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully — federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed — it helps clarify scope and scoring priorities.

Award Range

Up to $450,000

Close Date

May 7, 2026

Posted

November 25, 2024

Est. Total Funding

$225,000

Instrument

Grant

Description

The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. This includes integration of effective prevention and treatment interventions with an understanding of the overarching framework for reducing the incidence of new infections by facilitating cross-cutting informative research. This R34 Notice of Funding Opportunity (NOFO) supports studies that are both necessary and sufficient to inform the planning of a clinical trial within the scope of the companion announcement HIV Prevention and Alcohol (R01 Clinical Trials Optional). The NIAAA expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the future trial without further studies. The planned Phase II, III, or IV trial must be primarily intended to test the efficacy, safety, clinical management, or implementation of intervention(s) in the prevention of HIV. In this NIAAA funding opportunity for pilot clinical trials the R34 mechanism is intended to provide new information that answers a scientific or operational question(s) which may be pragmatic in nature and, therefore, informs the final development of a clinical trial and testing of intervention tools.

Eligibility

00;01;02;04;05;06;07;08;11;12;13;20;22;23;25

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

NIH Grants Information<br/>grantsinfo@nih.gov

Key Dates

Posted November 25, 2024
Close Date May 7, 2026
Archive Date June 12, 2026
Last Updated November 25, 2024

Frequently Asked Questions

What is this grant opportunity?
This is a federal funding opportunity titled "HIV Prevention and Alcohol (R34 Clinical Trials Optional)", offered by National Institutes of Health. It is associated with CFDA program 93.273. The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HI...
Is this opportunity still open?
Yes, this opportunity is currently open for applications. The closing date is May 7, 2026.
How much funding is available?
The award range for this opportunity is Up to $450,000. Total estimated funding: $225,000.
How do I apply?
Applications for federal grant opportunities are typically submitted through Grants.gov. Visit the official listing at grants.gov for application instructions, required documents, and submission deadlines.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainGrants Editorial