Open · PAR-26-116 · CFDA 93.313 · Discretionary

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

Federal grant opportunity posted by National Institutes of Health, cataloged on Grants.gov.

up to $500K
Award range
Open
Status
221d
Days left
-
Expected awards

The verdict

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) is an open discretionary opportunity from National Institutes of Health, offering Up to $500,000. Applications close in 221 days.

up to $500K
award range
Open
221 days left
93.313
CFDA program

Opportunity snapshot. This Grants.gov announcement - Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) - is cataloged under number PAR-26-116 and tied to CFDA assistance listing 93.313, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on December 8, 2025. The funding category is Discretionary, delivered as a cooperative agreement.

Award economics. The award range on file is Up to $500,000. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. Applications close on March 6, 2027 - roughly 221 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.

Award Range

Up to $500,000

Close Date

March 6, 2027

Posted

December 8, 2025

Instrument

Cooperative Agreement

Description

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

Eligibility

Grants.gov lists this opportunity under eligibility category codes 00, 01, 02, 04, 05, 06, 07, 08, 11, 12, 13, 20, 22, 23, 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

David J. Eckstein, PhD ClinicalCtrPartner@mail.nih.gov

Key Dates

Posted December 8, 2025
Close Date March 6, 2027
Archive Date April 10, 2027
Last Updated December 8, 2025

Frequently Asked Questions

What is this grant opportunity?
This is a federal funding opportunity titled "Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)", offered by National Institutes of Health. It is associated with CFDA program 93.313. The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that...
Is this opportunity still open?
Yes, this opportunity is currently open for applications. The closing date is March 6, 2027.
How much funding is available?
The award range for this opportunity is Up to $500,000.
How do I apply?
Applications for federal grant opportunities are typically submitted through Grants.gov. Visit the official listing at grants.gov for application instructions, required documents, and submission deadlines.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Data sourced from the SAM.gov Assistance Listings and Grants.gov. See our methodology for details. Retrieved and formatted by PlainGrants Editorial