Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)

Opportunity snapshot. This Grants.gov announcement — Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed) — is cataloged under number RFA-AI-27-019 and tied to CFDA assistance listing 93.855, posted by National Institutes of Health. Grants.gov currently shows the opportunity as open, first posted on February 10, 2026. The funding category is Discretionary, delivered as a cooperative agreement.

Award economics. The award range on file is Up to $3,000,000. The agency has projected $9.6 million in total estimated funding for this announcement. It expects to issue 3 awards. If the agency funds the expected 3 awards from the $9.6 million estimated pool, the average award works out to roughly $3.2 million. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. Applications close on June 4, 2026. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully — federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed — it helps clarify scope and scoring priorities.