| Race to the Top CFDA 84.407 | U.S. Department of Education | $50.0M |
| Race to the Top — Early Learning Challenge CFDA 84.411 | U.S. Department of Education | $100.0M |
| Rail Capital Assistance CFDA 20.320 | U.S. Department of Transportation | $500.0M |
| Railroad Crossing Elimination Program CFDA 20.316 | U.S. Department of Transportation | $100.0M |
| RAISE (Rebuilding American Infrastructure with Sustainability and Equity) CFDA 20.933 | U.S. Department of Transportation | $25.0M |
| Reading First CFDA 84.357 | U.S. Department of Education | $15.0M |
| Ready to Learn Television CFDA 84.295 | U.S. Department of Education | $15.0M |
| Recompete Pilot Program CFDA 11.312 | U.S. Department of Commerce | $200.0M |
| ReConnect Broadband Program CFDA 10.864 | U.S. Department of Agriculture | $25.0M |
| Reentry Employment Opportunities CFDA 17.268 | U.S. Department of Labor | $5.0M |
| Refugee and Entrant Assistance — Discretionary Grants CFDA 93.566 | U.S. Department of Health and Human Services | $5.0M |
| Registered Apprenticeship CFDA 17.720 | U.S. Department of Labor | $5.0M |
| Rehabilitation Research and Training Centers CFDA 84.264 | U.S. Department of Education | $3.0M |
| Rehabilitation Services Vocational Rehabilitation CFDA 84.126 | U.S. Department of Education | $20.0M |
| Rehabilitation Short-Term Training CFDA 84.246 | U.S. Department of Education | $500K |
| Rehabilitation Training CFDA 84.129 | U.S. Department of Education | $1.0M |
| Reintegration for Ex-Offenders Adult CFDA 17.265 | U.S. Department of Labor | $5.0M |
| Reintegration of Ex-Offenders CFDA 17.270 | U.S. Department of Labor | $3.0M |
| Rental Housing Integrity Improvement Project CFDA 14.182 | U.S. Department of Housing and Urban Development | $2.0M |
| Research and Training in Sleep Medicine CFDA 93.213 | National Institutes of Health | $1.0M |
| Research Experiences for Undergraduates (REU) CFDA 47.040 | National Science Foundation | $500K |
| Research in Special Education CFDA 84.324 | U.S. Department of Education | $2.0M |
| Research on Healthcare Costs, Quality and Outcomes CFDA 93.173 | U.S. Department of Health and Human Services | $5.0M |
| Research Opportunity Awards CFDA 47.049 | National Science Foundation | $500K |
| Research, Development, Monitoring, Public Education, Outreach CFDA 66.716 | U.S. Environmental Protection Agency | $3.0M |
| Residential Substance Abuse Treatment for State Prisoners CFDA 16.741 | U.S. Department of Justice | $2.0M |
| Residential Substance Abuse Treatment — Juvenile CFDA 16.593 | U.S. Department of Justice | $1.0M |
| Rural Business Development Grants CFDA 10.886 | U.S. Department of Agriculture | $500K |
| Rural Community Development Initiative CFDA 10.442 | U.S. Department of Agriculture | $750K |
| Rural Development Business Grants CFDA 10.407 | U.S. Department of Agriculture | $500K |
| Rural Education Achievement Program CFDA 84.358 | U.S. Department of Education | $1.0M |
| Rural Health Care Services Outreach CFDA 93.912 | U.S. Department of Health and Human Services | $750K |
| Rural Housing and Economic Development CFDA 14.868 | U.S. Department of Housing and Urban Development | $1.5M |
| Rural Housing Loans CFDA 10.433 | U.S. Department of Agriculture | $600K |