Closed · DE-FOA-0003281 · CFDA 81.049 · Discretionary
Integrated Biological and Computational Low-Dose Radiation Research
Federal grant opportunity posted by Office of Science, cataloged on Grants.gov.
- $750K-$1.5M
- Award range
- Closed
- Status
- April 2, 2024
- Close date
- -
- Expected awards
The verdict
Integrated Biological and Computational Low-Dose Radiation Research is a closed discretionary listing from Office of Science that offered $750,000 -- $1,500,000. Future funding cycles may be published under the same CFDA number.
- $750K-$1.5M
- award range
- Closed
- application status
- 81.049
- CFDA program
Opportunity snapshot. This Grants.gov announcement - Integrated Biological and Computational Low-Dose Radiation Research - is cataloged under number DE-FOA-0003281 and tied to CFDA assistance listing 81.049, posted by Office of Science. Grants.gov currently shows the opportunity as closed, first posted on December 21, 2023. The funding category is Discretionary, delivered as a grant.
Award economics. The award range on file is $750,000 -- $1,500,000. The agency has projected $18.0 million in total estimated funding for this announcement. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.
Deadline and action path. This opportunity closed on April 2, 2024. Future funding cycles may be published under the same CFDA number, so monitoring the parent program page is the most reliable way to catch re-announcements. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully, federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed, it helps clarify scope and scoring priorities. Before acting on the deadline or award figures above, verify them directly on the official Grants.gov listing, amendments can change dates and amounts after this page was last refreshed.
Award Range
$750,000 -- $1,500,000
Close Date
April 2, 2024
Posted
December 21, 2023
Est. Total Funding
$18,000,000
Instrument
Grant
Description
DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in development of integrated biological and computational research to gain a mechanistic understanding of the effects of low dose radiation exposure on cellular functions. The long-term goal is to build on the understanding of radiation effects on cellular function and establish comprehensive datasets amenable to incorporation into increasingly capable AI/ML models to identify both transient and persistent changes in cellular metabolism that may be linked to adverse health outcomes. This announcement builds on BER’s past efforts in low dose radiation research but seeks to take advantage of rapid technological changes in high throughput genomics, ‘omics and computational (Artificial Intelligence and Machine Learning [AI/ML]) technologies in recent years to advance a more mechanistic understanding of low dose and low dose rate effects on cellular metabolism. Developing a large compendium of high-quality datasets coupled with advances in AI/ML computational techniques trained on such data and integrated within the larger scientific literature on cellular processes affords the ability to explore a more mechanistic understanding of the impact low dose radiation has on cellular function. Over the long-term, this approach can provide a mechanistic basis for identifying markers and/or patterns in altered cellular function that may be indicative of or associated with an adverse health outcome. These approaches may also provide new insights into the uncertainties of health effects seen in epidemiological studies due to low dose radiation exposure and provide a basis to explore links to health effects other than cancer.
Eligibility
Grants.gov lists this opportunity under eligibility category code 25. These codes correspond to applicant types (state/local government, tribal organization, nonprofit, educational institution, individual, small business, etc.) defined in Grants.gov's own eligibility reference. See the current Grants.gov eligibility categories or check the official listing below for this opportunity's exact eligibility statement.
Official Listing on Grants.gov
View full details, application forms, and submission instructions.
Parent Grant Program
Basic Energy Sciences
U.S. Department of Energy
Agency Contact
SC.GrantsandContracts@science.doe.gov
Key Dates
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| Sources | the SAM.gov Assistance Listings and Grants.gov |