Open DE-FOA-0003600 CFDA 81.049 Discretionary

FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program

Posted by Office of Science

Opportunity snapshot. This Grants.gov announcement — FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program — is cataloged under number DE-FOA-0003600 and tied to CFDA assistance listing 81.049, posted by Office of Science. Grants.gov currently shows the opportunity as open, first posted on September 30, 2025 and last updated on December 16, 2025. The funding category is Discretionary, delivered as a other.

Award economics. The award range on file is $50,000 -- $5,000,000. The agency has projected $500.0 million in total estimated funding for this announcement. It expects to issue 500 awards. If the agency funds the expected 500 awards from the $500.0 million estimated pool, the average award works out to roughly $1.0 million. Cost sharing is not required, so applicants do not need to commit matching funds to be competitive on this opportunity. Federal award ranges are often upper bounds; actual allocations reflect program appropriations, the strength of the applicant pool, and the evaluation committee's scoring.

Deadline and action path. Applications close on September 30, 2026 — roughly 117 days from today. Every Grants.gov submission requires an active SAM.gov registration and a Unique Entity ID. Review the Eligibility section below carefully — federal eligibility categories (nonprofit, state or local government, tribal, individual, educational institution, small business) have distinct registration and reporting requirements. Pre-application outreach to the listed agency contact is permitted and often welcomed — it helps clarify scope and scoring priorities.

Award Range

$50,000 -- $5,000,000

Close Date

September 30, 2026

Posted

September 30, 2025

Est. Total Funding

$500,000,000

Expected Awards

500

Instrument

Other

Description

The Office of Science (SC) of the Department of Energy (DOE) hereby announces its continuing interest in receiving applications for support of work in the following program areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. On September 3, 1992, DOE published in the Federal Register the Office of Energy Research Financial Assistance Program (now called the Office of Science Financial Assistance Program), 10 CFR 605, as a Final Rule, which contained a solicitation for this program. Information about submission of applications, eligibility, limitations, evaluation and selection processes and other policies and procedures are specified in 10 CFR 605. This NOFO is our annual open solicitation that covers all research areas in SC and is open throughout the Fiscal Year. Any research within SC’s Congressionally authorized mission may be proposed under this NOFO. This NOFO will remain open until September 30, 2026, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first. This NOFO succeeds DE-FOA-0003432, which was published September 30, 2024.

Eligibility

99

Official Listing on Grants.gov

View full details, application forms, and submission instructions.

View on Grants.gov

Agency Contact

sc.opencall@science.doe.gov

Key Dates

Posted September 30, 2025
Close Date September 30, 2026
Archive Date October 30, 2026
Last Updated December 16, 2025

Frequently Asked Questions

What is this grant opportunity?
This is a federal funding opportunity titled "FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program", offered by Office of Science. It is associated with CFDA program 81.049. The Office of Science (SC) of the Department of Energy (DOE) hereby announces its continuing interest in receiving applications for support of work in the following program areas: Advanced Scientific ...
Is this opportunity still open?
Yes, this opportunity is currently open for applications. The closing date is September 30, 2026.
How much funding is available?
The award range for this opportunity is $50,000 -- $5,000,000. Total estimated funding: $500,000,000. Expected number of awards: 500.
How do I apply?
Applications for federal grant opportunities are typically submitted through Grants.gov. Visit the official listing at grants.gov for application instructions, required documents, and submission deadlines.

Disclaimer: This information is sourced from Grants.gov and SAM.gov and is for informational purposes only. Opportunity details, deadlines, and eligibility requirements change frequently. Always verify current information directly on Grants.gov before applying. PlainGrants is not affiliated with any federal agency.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainGrants Editorial