| Bureau of Land Management Grants CFDA 15.560 | U.S. Department of the Interior | Environment | $3.0M |
| Bus and Bus Facilities Formula Grants CFDA 20.526 | U.S. Department of Transportation | Transportation | $50.0M |
| Cancer Control CFDA 93.399 | Centers for Disease Control and Prevention | Health | $5.0M |
| Cancer Prevention Research CFDA 93.847 | National Institutes of Health | Health | $3.0M |
| Cancer Research Grants CFDA 93.393 | National Institutes of Health | Health | $3.0M |
| Cancer Treatment Research CFDA 93.395 | National Institutes of Health | Health | $5.0M |
| Capital Assistance for Innovative Mobility CFDA 20.520 | U.S. Department of Transportation | Transportation | $10.0M |
| Capital Magnet Fund CFDA 11.020 | U.S. Department of Commerce | Business & Economic Development | $15.0M |
| Capitalization Grants for Drinking Water CFDA 66.468 | U.S. Environmental Protection Agency | Environment | $200.0M |
| Career and Technical Education State Grants (Perkins) CFDA 84.048 | U.S. Department of Education | Education | $20.0M |
| Carl D. Perkins Career and Technical Education Improvement CFDA 84.048 | U.S. Department of Education | Education | $20.0M |
| Centers for Disease Control Investigations and Technical Assistance CFDA 93.283 | Centers for Disease Control and Prevention | Health | $5.0M |
| Centers for Independent Living CFDA 84.132 | U.S. Department of Education | Education | $1.0M |
| Centers of Excellence CFDA 93.157 | U.S. Department of Health and Human Services | Health | $2.0M |
| Challenge America CFDA 45.024 | National Endowment for the Arts | Arts & Culture | $10K |
| Charter Schools CFDA 84.282 | U.S. Department of Education | Education | $10.0M |
| Child Care and Development Block Grant CFDA 93.575 | U.S. Department of Health and Human Services | Health | $100.0M |
| Child Care Mandatory and Matching Funds CFDA 93.596 | U.S. Department of Health and Human Services | Health | $50.0M |
| Child Support Enforcement CFDA 93.563 | U.S. Department of Health and Human Services | Health | $50.0M |
| Child Welfare Services — State Grants CFDA 93.645 | U.S. Department of Health and Human Services | Health | $20.0M |
| Childhood Lead Poisoning Prevention CFDA 93.197 | Centers for Disease Control and Prevention | Health | $2.0M |
| Children's Health Insurance Program (CHIP) Grants CFDA 93.767 | U.S. Department of Health and Human Services | Health | $500.0M |
| Choice Neighborhoods Implementation Grants CFDA 14.871 | U.S. Department of Housing and Urban Development | Housing | $50.0M |
| Chronic Disease Prevention Health Promotion CFDA 93.048 | Centers for Disease Control and Prevention | Health | $5.0M |
| Citizen Corps CFDA 97.053 | Federal Emergency Management Agency | Public Safety | $500K |
| Clean Water State Revolving Funds CFDA 66.483 | U.S. Environmental Protection Agency | Environment | $500.0M |
| Coastal Zone Management Administration Awards CFDA 11.472 | National Oceanic and Atmospheric Administration | Environment | $5.0M |
| Coastal Zone Management Estuarine Reserve CFDA 11.415 | National Oceanic and Atmospheric Administration | Business & Economic Development | $5.0M |
| Commodity Loans and Loan Deficiency Payments CFDA 10.051 | U.S. Department of Agriculture | Agriculture | $500K |
| Community Access and Veterans Access CFDA 64.232 | U.S. Department of Veterans Affairs | Health | $1.0M |
| Community Advantage Loans CFDA 59.072 | U.S. Small Business Administration | Business & Economic Development | $5.0M |
| Community Challenge Planning Grants CFDA 14.318 | U.S. Department of Housing and Urban Development | Housing | $3.0M |
| Community Development Block Grant (CDBG) CFDA 14.218 | U.S. Department of Housing and Urban Development | Housing | $20.0M |
| Community Development Block Grants — State Program CFDA 14.228 | U.S. Department of Housing and Urban Development | Housing | $10.0M |
| Community Development Block Grants — Technical Assistance CFDA 14.219 | U.S. Department of Housing and Urban Development | Housing | $1.0M |
| Community Economic Adjustment Assistance CFDA 11.002 | U.S. Department of Commerce | Business & Economic Development | $5.0M |
| Community Facilities Loans and Grants CFDA 10.766 | U.S. Department of Agriculture | Agriculture | $2.0M |
| Community Health Centers CFDA 93.527 | U.S. Department of Health and Human Services | Health | $10.0M |
| Community Resilience Corps CFDA 97.131 | Federal Emergency Management Agency | Public Safety | $1.0M |
| Community Services Block Grant CFDA 93.569 | U.S. Department of Health and Human Services | Health | $20.0M |
| Community Services for Older Adults CFDA 97.097 | U.S. Department of Health and Human Services | Public Safety | $3.0M |
| Comprehensive Behavioral Health Programs CFDA 93.153 | U.S. Department of Health and Human Services | Health | $3.0M |
| Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program CFDA 16.523 | U.S. Department of Justice | Public Safety | $2.0M |
| Comprehensive School Safety Initiative CFDA 16.034 | U.S. Department of Justice | Public Safety | $5.0M |
| Computer and Information Science and Engineering CFDA 47.070 | National Science Foundation | Science & Research | $3.0M |
| Congressionally Mandated Projects CFDA 66.202 | U.S. Environmental Protection Agency | Environment | $5.0M |
| Connecting People to Collections CFDA 45.310 | Institute of Museum and Library Services | Arts & Culture | $250K |
| Conservation Research and Development CFDA 81.086 | U.S. Department of Energy | Science & Research | $2.0M |
| Conservation Reserve Program (CRP) CFDA 10.069 | U.S. Department of Agriculture | Agriculture | $200K |
| Consolidated Health Centers CFDA 93.230 | U.S. Department of Health and Human Services | Health | $8.0M |