| Greenhouse Gas Reduction Fund CFDA 66.054 | U.S. Environmental Protection Agency | Environment | $7.0B |
| Guardianship Assistance Program CFDA 93.090 | U.S. Department of Health and Human Services | Health | $10.0M |
| H-1B Technical Skills Training Grants CFDA 17.804 | U.S. Department of Labor | Education | $10.0M |
| Head Start CFDA 93.600 | U.S. Department of Health and Human Services | Health | $20.0M |
| Health Care and Other Facilities CFDA 93.887 | U.S. Department of Health and Human Services | Health | $3.0M |
| Health Care Facilities Cooperation CFDA 93.226 | U.S. Department of Health and Human Services | Health | $3.0M |
| Health Center Fund CFDA 93.129 | U.S. Department of Health and Human Services | Health | $10.0M |
| Health Centers Loan Guarantee CFDA 93.224 | U.S. Department of Health and Human Services | Health | $5.0M |
| Health Professions Recruitment CFDA 93.925 | U.S. Department of Health and Human Services | Health | $2.0M |
| Healthy Communities Grants CFDA 93.932 | Centers for Disease Control and Prevention | Health | $5.0M |
| Healthy Communities Grants CFDA 66.110 | U.S. Environmental Protection Agency | Environment | $2.0M |
| Healthy Homes Production Grants CFDA 14.885 | U.S. Department of Housing and Urban Development | Housing | $2.0M |
| Healthy Homes Technical Studies CFDA 14.886 | U.S. Department of Housing and Urban Development | Housing | $1.5M |
| Healthy Start Initiative CFDA 93.301 | U.S. Department of Health and Human Services | Health | $3.0M |
| Heart and Vascular Disease Research CFDA 93.837 | National Institutes of Health | Health | $3.0M |
| High-Speed Rail Corridors and Intercity Passenger Rail Service CFDA 20.318 | U.S. Department of Transportation | Transportation | $1.0B |
| Higher Education Facilities Loans and Insurance CFDA 84.093 | U.S. Department of Education | Education | $20.0M |
| Higher Education Institutional Aid CFDA 84.031 | U.S. Department of Education | Education | $5.0M |
| Highway Planning and Construction CFDA 20.205 | U.S. Department of Transportation | Transportation | $500.0M |
| Highway Safety Improvement Program CFDA 20.930 | U.S. Department of Transportation | Transportation | $100.0M |
| Hispanic-Serving Agricultural Colleges and Universities Program CFDA 10.446 | U.S. Department of Agriculture | Agriculture | $3.0M |
| Historic Preservation Fund Grants-in-Aid CFDA 15.904 | U.S. Department of the Interior | Environment | $5.0M |
| HIV Care Formula Grants (Ryan White Part B) CFDA 93.917 | U.S. Department of Health and Human Services | Health | $30.0M |
| HIV Emergency Relief Project Grants CFDA 93.914 | U.S. Department of Health and Human Services | Health | $50.0M |
| HIV Prevention Activities — Health Department Based CFDA 93.940 | Centers for Disease Control and Prevention | Health | $20.0M |
| HIV/AIDS Surveillance CFDA 93.704 | Centers for Disease Control and Prevention | Health | $5.0M |
| HOME Investment Partnerships CFDA 14.239 | U.S. Department of Housing and Urban Development | Housing | $5.0M |
| Homeland Security Grant Program CFDA 97.067 | Federal Emergency Management Agency | Public Safety | $10.0M |
| Housing Counseling Assistance CFDA 14.169 | U.S. Department of Housing and Urban Development | Housing | $1.0M |
| Housing Opportunities for Persons with AIDS (HOPWA) CFDA 14.241 | U.S. Department of Housing and Urban Development | Housing | $3.0M |
| HUBZone Program CFDA 59.037 | U.S. Small Business Administration | Business & Economic Development | $0 |
| Hydrogen and Fuel Cell Technologies CFDA 81.049 | U.S. Department of Energy | Science & Research | $5.0M |
| IMLS Inspire! Grants for Small Museums CFDA 45.308 | Institute of Museum and Library Services | Arts & Culture | $75K |
| Imls Museums for America CFDA 45.310 | Institute of Museum and Library Services | Arts & Culture | $250K |
| IMLS National Digital Platform CFDA 45.316 | Institute of Museum and Library Services | Arts & Culture | $2.0M |
| Immunization Cooperative Agreements CFDA 93.268 | Centers for Disease Control and Prevention | Health | $20.0M |
| Impact Aid CFDA 84.051 | U.S. Department of Education | Education | $10.0M |
| Improving Literacy Through School Libraries CFDA 84.361 | U.S. Department of Education | Education | $2.0M |
| Improving Teacher Quality State Grants CFDA 84.367 | U.S. Department of Education | Education | $25.0M |
| Independent Living State Grants CFDA 84.169 | U.S. Department of Education | Education | $2.0M |
| Indian Education Discretionary Grants CFDA 84.060 | U.S. Department of Education | Education | $1.0M |
| Indian Education Formula Grants CFDA 84.059 | U.S. Department of Education | Education | $2.0M |
| Indian Tribes and Tribal Corporations — Loans CFDA 10.352 | U.S. Department of Agriculture | Agriculture | $300K |
| Industry and Sector Partnerships CFDA 17.207 | U.S. Department of Labor | Education | $5.0M |
| Innovative Approaches to Literacy CFDA 84.421 | U.S. Department of Education | Education | $5.0M |
| Integrated Mobility Innovation CFDA 20.533 | U.S. Department of Transportation | Transportation | $5.0M |
| Integrated Programs CFDA 10.303 | U.S. Department of Agriculture | Agriculture | $2.0M |
| Integrative Organismal Systems CFDA 47.049 | National Science Foundation | Science & Research | $1.0M |
| Intergovernmental Climate Change Adaptation CFDA 11.426 | National Oceanic and Atmospheric Administration | Environment | $2.0M |
| International Science and Engineering Research CFDA 47.079 | National Science Foundation | Science & Research | $1.0M |