| Investing in Innovation Fund (i3) CFDA 84.417 | U.S. Department of Education | Education | $50.0M |
| Investments for Public Works and Economic Development CFDA 11.300 | U.S. Department of Commerce | Business & Economic Development | $10.0M |
| Javits Gifted and Talented Students Education CFDA 84.101 | U.S. Department of Education | Education | $3.0M |
| Job Access and Reverse Commute CFDA 20.516 | U.S. Department of Transportation | Transportation | $5.0M |
| John R. Justice Grant Program CFDA 16.816 | U.S. Department of Justice | Public Safety | $1.0M |
| Justice Assistance Grant (JAG) CFDA 16.738 | U.S. Department of Justice | Public Safety | $10.0M |
| Juvenile Justice Formula Grants CFDA 16.540 | U.S. Department of Justice | Public Safety | $20.0M |
| Laura Bush 21st Century Librarian Program CFDA 45.312 | Institute of Museum and Library Services | Arts & Culture | $500K |
| Lead Hazard Reduction Demonstration Grant CFDA 14.914 | U.S. Department of Housing and Urban Development | Housing | $4.0M |
| Lead-Based Paint Hazard Control CFDA 14.400 | U.S. Department of Housing and Urban Development | Housing | $5.0M |
| Lifespan Respite Care Program CFDA 93.734 | U.S. Department of Health and Human Services | Health | $2.0M |
| Livestock Forage Disaster Program CFDA 10.088 | U.S. Department of Agriculture | Agriculture | $100K |
| Loan Repayment for Mental Health Practitioners CFDA 93.232 | U.S. Department of Health and Human Services | Health | $130K |
| Local Housing Assistance Program CFDA 14.256 | U.S. Department of Housing and Urban Development | Housing | $3.0M |
| Lung Disease Research CFDA 93.838 | National Institutes of Health | Health | $3.0M |
| Magnet Schools Assistance CFDA 84.228 | U.S. Department of Education | Education | $15.0M |
| Major Research Instrumentation Program CFDA 47.049 | National Science Foundation | Science & Research | $4.0M |
| Maternal and Child Health Block Grant CFDA 93.994 | U.S. Department of Health and Human Services | Health | $30.0M |
| Maternal and Child Health Federal Consolidated Programs CFDA 93.110 | U.S. Department of Health and Human Services | Health | $5.0M |
| Maternal, Infant, and Early Childhood Home Visiting CFDA 93.870 | U.S. Department of Health and Human Services | Health | $10.0M |
| Mathematical and Physical Sciences CFDA 47.049 | National Science Foundation | Science & Research | $2.0M |
| Mathematics and Science Partnerships CFDA 84.386 | U.S. Department of Education | Education | $5.0M |
| McNair Post-Baccalaureate Achievement CFDA 84.217 | U.S. Department of Education | Education | $700K |
| Medicaid HCBS Grants CFDA 93.778 | U.S. Department of Health and Human Services | Health | $50.0M |
| Medicaid Transformation Grants CFDA 93.791 | U.S. Department of Health and Human Services | Health | $50.0M |
| Medical Assistance Program (Medicaid) CFDA 93.778 | U.S. Department of Health and Human Services | Health | $5.0B |
| Medical Library Assistance CFDA 93.879 | National Institutes of Health | Health | $1.0M |
| Mental Health National Research Service Awards CFDA 93.350 | National Institutes of Health | Health | $60K |
| Mental Health Research Grants CFDA 93.242 | National Institutes of Health | Health | $5.0M |
| Mental Health Service Professional Demonstration Program CFDA 84.424 | U.S. Department of Education | Education | $5.0M |
| Microloan Program CFDA 59.046 | U.S. Small Business Administration | Business & Economic Development | $5.0M |
| Migrant Education Basic State Formula Grants CFDA 84.011 | U.S. Department of Education | Education | $5.0M |
| Migratory Bird Conservation Grant CFDA 15.657 | U.S. Department of the Interior | Environment | $3.0M |
| Milk Income Loss Contract Program CFDA 10.108 | U.S. Department of Agriculture | Agriculture | $50K |
| Minority Business Development CFDA 11.557 | U.S. Department of Commerce | Business & Economic Development | $2.0M |
| Minority Health and Health Disparities Research CFDA 93.307 | National Institutes of Health | Health | $3.0M |
| Minority Science and Engineering Improvement Program CFDA 84.120 | U.S. Department of Education | Education | $500K |
| Minority Serving Institutions Digital and Technology Opportunity Program CFDA 11.022 | U.S. Department of Commerce | Business & Economic Development | $3.0M |
| Missing Children's Assistance CFDA 16.543 | U.S. Department of Justice | Public Safety | $3.0M |
| Mortgage Insurance for Rental Housing CFDA 14.151 | U.S. Department of Housing and Urban Development | Housing | $50.0M |
| Multifamily Housing Revitalization CFDA 14.313 | U.S. Department of Housing and Urban Development | Housing | $10.0M |
| Multifamily Housing Service Coordinators CFDA 14.267 | U.S. Department of Housing and Urban Development | Housing | $1.0M |
| Museum and Library Services — Basic Library Services CFDA 45.301 | Institute of Museum and Library Services | Arts & Culture | $20.0M |
| Museum Grants for African American History and Culture CFDA 45.308 | Institute of Museum and Library Services | Arts & Culture | $300K |
| Museums for America Grants CFDA 45.313 | Institute of Museum and Library Services | Arts & Culture | $500K |
| NASA University Research Initiative CFDA 43.009 | National Aeronautics and Space Administration | Science & Research | $5.0M |
| National Cancer Institute SBIR CFDA 93.300 | National Institutes of Health | Health | $2.0M |
| National Center on Sleep Disorders Research CFDA 93.233 | National Institutes of Health | Health | $1.0M |
| National Criminal History Improvement Program CFDA 16.556 | U.S. Department of Justice | Public Safety | $5.0M |
| National Diabetes Prevention Program CFDA 93.048 | Centers for Disease Control and Prevention | Health | $3.0M |